< Nota - Show Notes for Huberman Lab - Episode: The Effects of Cannabis (Marijuana) on the Brain & Body
View notes for Podcast: Huberman Lab
Oct 3, 2022

The Effects of Cannabis (Marijuana) on the Brain & Body

In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its ...  impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful.

Inspired by Mary Jane? Mechanisms underlying enhanced creativity in cannabis users

Sober cannabis users showed enhanced self-reported creativity to non-users. * Sober cannabis users demonstrated superior convergent thinking ability to non-users. * Cannabis users were more extraverted, open to experience and less conscientious. * Differences in openness to experience explained cannabis users' enhanced creativity.
Sciencedirect

Adults with a history of recreational cannabis use have altered speech production

Stereotypical depictions of speech in cannabis users often suggest slow, laboured output, yet objective evidence supporting this assumption is extremely limited. We know that depressants or hallucinogenic drugs such as cannabis can cause acute changes in communication and speech rate, but the long-lasting effects of cannabis use on speech are not well described.
Sciencedirect

Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study - Psychopharmacology

Rationale Self-report studies indicate that cannabis could increase sexual desire in some users. We hypothesized that intoxication increases activation of brain areas responsive to visual erotica, which could be useful in the treatment of hypoactive sexual desire disorder, a condition marked by a lack of sexual desire.
SpringerLink

Bayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning - Translational Psychiatry

While there is substantial evidence that cannabis use is associated with differences in human brain development, most of this evidence is correlational in nature. Bayesian causal network (BCN) modeling attempts to identify probable causal relationships in correlational data using conditional probabilities to estimate directional associations between a set of interrelated variables.
Nature

Association of cannabis potency with mental ill health and addiction: a systematic review

Cannabis potency, defined as the concentration of THC, has increased internationally, which could increase the risk of adverse health outcomes for cannabis users.
The Lancet Psychiatry

Huberman Lab Premium

Become a Huberman Lab Premium Subscriber. By subscribing, you'll get access to ask Dr. Huberman questions, exclusive bonus content (AMA episodes and Quantal clips) and episode transcripts. A significant portion of proceeds will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.
Supercast

Non-Sleep Deep Rest (#NSDR) Protocol

In this 10-minute meditation, Dr. Andrew Huberman guides you through a non-sleep deep rest protocol (NSDR) to enhance the learning process by reducing day-time fatigue and improving focus. It can also greatly enhance your sleep, boost your mood, and promote neuroplasticity.
YouTube

Official Episode Page

Get more podcast show notes and content direct from the Huberman Lab website.
Huberman Lab